Response of Discoid and Subacute Cutaneous Lupus Erythematosus to Recombinant Interferon Alpha 2A

Chronic cutaneous (discoid) lupus erythematosus.

Linear cutaneous lupus erythematosus/discoid lupus erythematosus in an adult

Linear cutaneous lupus erythematosus (LCLE) is rare. The LCLE was proposed by Abe et al. [1] for discoid lupus erythematosus (DLE) with a linear configuration in 1988. It occurs mainly in children and young adults. Lesions appear as linear unilateral erythematous plaques following the Blaschko lines and are observed most frequently on the face, although the neck, trunk and extremities may also ...

[Refractory subacute cutaneous lupus erythematosus with a response to efalizumab].

Actas Dermosifiliogr. 2009;100:719-40 734 5. Gurrieri F, Franco B, Toriello H, Neri G. Oral-facial-digital syndromes: review and diagnostic guidelines. Am J Med Genet. 2007;143:3314-23. 6. Rimoin DL, Edgerton MT. Genetic and c linical heterogeneity in the oral-facial-digital syndrome. J Pediatr. 1967;71:94-102. 7. Anneren G, Arvidson B, Gustavson KH, Jorulf H, Carlsson G. Oral-facial-digital sy...

Pathogenesis of subacute cutaneous lupus erythematosus.

Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive form of lupus-specific skin lesion that is strongly associated with the presence of anti-Ro/SSA autoantibody. The pathogenesis of SCLE includes genetic, environmental and immunologic factors. Recent studies provide strong evidence for the involvement of innate and cell-mediated immunity, underlying the important role of plasmacyt...

Anastrozole-induced subacute cutaneous lupus erythematosus.

Drug-induced subacute cutaneous lupus erythematosus (DI-SCLE) has been associated with numerous drugs, but there are limited reports of its association with aromatase inhibitor anastrozole. We report the case of a patient undergoing treatment with anastrozole for breast cancer who presented with clinical, serological, and histological evidence consistent with DI-SCLE. Her condition quickly bega...